Annatto-E® Synergy

Tocotrienol and Black Cumin Seed Support for Cardiovascular Health, Metabolic Function, and Full-Body Wellness*

Key Performance Benefits

• Promotes cardiovascular health and normal cholesterol and triglyceride metabolism*

• Supports antioxidant status and healthy inflammatory responses*

• Supports metabolic health and normal body weight*

• Supports liver health*

• May help support respiratory and bone health*

• Promotes brain health and immune function*

What This Product Is

Annatto-E® Synergy features the preferred form of vitamin E (100% tocotrienols) combined with black cumin seed oil for comprehensive full-body support. Each two-softgel serving delivers 125 mg of DeltaGold® delta- and gamma-tocotrienols sourced from annatto along with 1 g of black cumin seed oil (Nigella sativa), creating a synergistic formula that promotes cardiovascular, metabolic, and immune health.*

Compared to alpha-tocopherols (another form of vitamin E), the delta- and gamma-tocotrienols in this product may promote metabolic health by supporting normal body weight and a healthy inflammatory response, which can be especially important for those concerned with liver health. The combination of tocotrienols and black cumin seed offers broader support than either ingredient alone, extending benefits to respiratory and bone health.*

Mechanism of Action

Cardiovascular and Metabolic Support

DeltaGold® tocotrienols promote normal cholesterol and triglyceride metabolism, supporting cardiovascular health. The delta- and gamma-tocotrienol forms may promote metabolic health by supporting normal body weight and healthy inflammatory responses, which is particularly relevant for liver health and overall metabolic function.*

Immune and Inflammatory Response

The active compound in black cumin seed, thymoquinone, promotes a healthy inflammatory response and supports immune system balance. Combined with the antioxidant properties of tocotrienols, this dual-action formula provides comprehensive support for the body’s inflammatory and immune pathways.*

Respiratory, Bone, and Brain Health

Black cumin seed provides support for normal respiratory health and lung function, while the combination of tocotrienols and black cumin seed may also support bone health. Annatto-E® Synergy additionally promotes brain health through the neuroprotective and antioxidant properties of both tocotrienols and black cumin seed compounds.*

Applications

• Individuals seeking comprehensive cardiovascular and metabolic health support*

• Those looking to support antioxidant status and healthy inflammatory responses*

• Individuals seeking to promote liver health and normal body weight*

• Those looking to support immune function and respiratory health*

• Individuals seeking synergistic tocotrienol and black cumin seed benefits for full-body wellness*

Key Ingredients / Formula Highlights

DeltaGold® Tocotrienols (125 mg per serving)

Delta- and gamma-tocotrienols derived from annatto seeds that promote metabolic, liver, cardiovascular, respiratory, and bone health. Vitamin E tocotrienols also support antioxidant status and healthy inflammatory responses.*

Black Cumin Seed Oil (1 g per serving)

Derived from Nigella sativa, a commonly used spice with a long history of supporting various health conditions. The active compound thymoquinone promotes a healthy inflammatory response, supports immune system balance, and provides support for normal respiratory health and lung function.*

Clean Formula Design

Gluten-free, dairy-free, soy-free, and non-GMO. Synergistic two-ingredient formula for comprehensive support.

Suggested Use

Take 2 softgels per day or as directed by your health-care practitioner.

Product Questions

Why are tocotrienols and black cumin seed combined in this formula?

Tocotrienols and black cumin seed offer complementary mechanisms of action that provide broader full-body support than either ingredient alone. Together they promote cardiovascular, metabolic, immune, respiratory, and bone health while supporting antioxidant status and healthy inflammatory responses.*

How does Annatto-E® Synergy differ from Annatto-E®?

Annatto-E® provides tocotrienols alone for focused vitamin E tocotrienol support, while Annatto-E® Synergy adds 1 g of black cumin seed oil for expanded benefits including immune system balance, respiratory health support, and enhanced inflammatory response modulation through the active compound thymoquinone.*

Who may benefit most from Annatto-E® Synergy?

Individuals seeking comprehensive full-body support may benefit, particularly those looking to promote cardiovascular and metabolic health, support liver function, maintain healthy inflammatory responses, and support immune and respiratory health through a synergistic tocotrienol and black cumin seed formula.*

Practitioner Reference

Annatto-E® Synergy is positioned within the Designs for Health Foundational Health category. Available as ANTS60 (60 softgels). This product is intended for use under the guidance of a licensed health-care practitioner.